Core fucosylation and IgG function in NAIT.
نویسنده
چکیده
In this issue of Blood, Kapur et al show that maternal human platelet-specific antigen 1a (HPA 1a)-specific antibodies causing neonatal alloimmune thrombocytopenia (NAIT) possess oligosaccharides that are deficient in "core fucose" residues and appear to be more effective than fucosylated antibodies in promoting phagocytosis of antibody-coated platelets.
منابع مشابه
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ورودعنوان ژورنال:
- Blood
دوره 123 4 شماره
صفحات -
تاریخ انتشار 2014